What is a proven way to loose weight?

I am 44 years old. 5'6 and 240lbs. I eat healthy. Moderate excersize to low excersize. I used to be aneorexic for 6 years in my 20's. My doctor suggests my body just wants to hold on to the fat now. I absolutely hate regimented excersize, hikes, or walks. I do have a problem with remembering to eat on a timely basis. It is not unusual for me to go 8 - 10 hours and not eat anything. But I try to remember to eat and I just can't be consistent with it. I tried Phen/Fen diet 10 years ago and lost 50 lbs which I gained right back with my last child who is now 9. (I am not worried about the health risk of Phen/Fen diet, doctors said I am fine) I really would like a "miracle" drug that would help me but they all have appetite supressants which I DON'T need. Please give me your ideas.